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KMID : 0358419940370112248
Korean Journal of Obstetrics and Gynecology
1994 Volume.37 No. 11 p.2248 ~ p.2256
The Prevalence of Human Papilomavirus in te Patients with Uterine Cervical Carcinoma Less than 36 Years Old


Abstract
Objectives:
@EN To evaluate the relationship between the prevalance and types of human papillomavirus, and clinical variants of the patients with cervical carcinoma less than 36 years old.
@ES Methods:
@EN Comparative analysis was undertaken with the clinical variants following detection of human papillomavirus by means of polymerase chain reactions with the primers of HPV L1 consensus, type 16 and 18, E6 and Southern blot hybridization (with
the
probes of HPV type 16 and 18) in the 20 patients less than 36 years old and 10 patients more than 44 years old.
@ES Results:
@EN 1) The prevalence rate and types of human papillomavirus were 16/20 (80%).14/16 (87.5%) with 16, 2 with 18 in the group of patients less than 36 years old, and 9/10, type 16 only in the group of patients more than 44 years old, 2) The
correlation
between type 18 of human papillomavirus and lymphnode metastasis was not conclusive, and the prognosis was good in all the patients who were not detected HPV viral finger print. 3) Human papillomavirus infection was not matched properly to the
epidemiologic variants. 4) The majority of patients was ignored the benefits of early detection screening program.
@ES Conclusion:
@EN Human papilloma virus infection is not conclusive to the developemnt and prognosis of the patients with uterine cervical carcinoma in the group of patients less than 36 years old, and rearmament of the early detection screening program should
be
operated immediately.
KEYWORD
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